Vitamin B Complex

What it is:
The first discovered B-vitamin (thiamine), a crucial coenzyme for energy metabolism and nerve function.

Why we use it:
• Energy Boost – Converts carbs into ATP (body’s energy currency)
• Nerve Health – Maintains myelin sheath integrity
• Cognitive Support – Prevents Wernicke-Korsakoff syndrome
• Heart Function – Regulates cardiac muscle contractions

Can be found in:
Whole grains, pork, legumes, and nutritional yeast.

The Losoki Difference:
Benfotiamine – A fat-soluble form with 5x higher bioavailability than standard thiamine, crosses blood-brain barrier for targeted neurological support.

What it is:
A water-soluble energy-converting coenzyme (FAD/FMN precursor), vital for cellular respiration and antioxidant defense. Recognizable by its vibrant yellow color.

Why we use it:
• Energy Production – Key for mitochondrial ATP synthesis
• Vision Protection – Reduces cataract risk by 33% (AJO 2019)
• Skin & Hair Health – Supports collagen synthesis and sebum regulation
• Antioxidant Recycling – Regenerates glutathione (master antioxidant)

Can be found in:
Organ meats, eggs, almonds, and fortified cereals.

The Losoki Difference:
Activated riboflavin 5'-phosphate (FMN) – 3x faster cellular uptake than standard B2. Enhanced with selenium for optimal glutathione peroxidase activity.

What it is:
A unique B-vitamin existing as nicotinic acid and nicotinamide, serving as the precursor for NAD+/NADH – the most essential coenzymes in human metabolism.

Why we use it:
• Cellular Energy – Powers 400+ enzymatic reactions via NAD+
• Cholesterol Balance – Lowers LDL by 15% while raising HDL (FDA-approved use)
• Skin Barrier – Improves ceramide synthesis for moisture retention
• DNA Repair – Supports PARP enzymes for genetic maintenance

Can be found in:
Turkey, peanuts, mushrooms, and fortified breads.

The Losoki Difference:
Flush-free niacin (inositol hexanicotinate) – Provides all benefits without skin flushing. Combined with chromium for enhanced lipid metabolism.

What it is:
The most structurally complex vitamin, containing cobalt (hence "cobalamin"), essential for nerve function, DNA synthesis, and red blood cell formation.

Why we use it:
• Neurological Health – Maintains myelin sheath integrity (nerve protection)
• Energy Metabolism – Converts food into usable cellular energy
• Mood Regulation – Lowers homocysteine linked to depression
• Vegan Necessity – Only found in animal-derived foods

Can be found in:
Clams, beef liver, salmon, and fortified nutritional yeast.

The Losoki Difference:
Methylcobalamin + Adenosylcobalamin – The two bioactive forms with:
✓ 89% higher retention than cyanocobalamin
✓ Direct cellular utilization (no liver conversion)
✓ Sublingual delivery for bypassing absorption issues

What it is:
The "beauty vitamin" – a sulfur-containing coenzyme critical for keratin production and fatty acid synthesis.

Why we use it:
• Hair & Nails – Increases keratin infrastructure hardness by 25%
• Skin Health – Boosts ceramide production for moisture barrier
• Metabolic Support – Helps convert food into energy (gluconeogenesis)
• Prenatal Care – Often deficient during pregnancy

Can be found in:
Egg yolks, almonds, sweet potatoes, and organ meats.

The Losoki Difference:
Bioactive d-biotin (not synthetic analogs) with:
✓ 10,000 mcg optimal dose for beauty benefits
✓ Enhanced with zinc for synergistic keratin support
✓ Vegan-certified fermentation-derived

What it is:
The "anti-stress vitamin" – core component of Coenzyme A (CoA), involved in 100+ metabolic pathways including energy production and hormone synthesis.

Why we use it:
• Skin Repair – Accelerates wound healing by 30% (Burns 2021)
• Stress Response – Supports adrenal gland function
• Cholesterol Metabolism – Aids LDL-to-bile acid conversion
• Hair Vitality – Reduces oxidative damage in hair follicles

Can be found in:
Chicken liver, avocados, sunflower seeds, and mushrooms.

The Losoki Difference:
Dexpanthenol (provitamin B5) –
✓ 20% better skin absorption than plain B5
✓ Combined with hyaluronic acid for hydration synergy
✓ Sustainably sourced from plant fermentation

What it is:
An essential nutrient-like compound that acts as a precursor for acetylcholine (key neurotransmitter) and phospholipids (cell membrane builders).

Why we use it:
• Brain Function – Enhances memory & learning by 28% (AJCN 2023)
• Liver Health – Prevents fat accumulation (NAFLD protection)
• Fetal Development – Critical for neural tube closure (needs increase 4x during pregnancy)
• Muscle Control – Supports acetylcholine-mediated contractions

Can be found in:
Egg yolks (especially pasture-raised), beef liver, and soy lecithin.

The Losoki Difference:
Cognizin® Citicoline –
✓ 2-in-1 compound (choline + cytidine) for 99% bioavailability
✓ Crosses blood-brain barrier directly
✓ Non-GMO and allergen-free

What it is:
A naturally occurring B-vitamin-like compound, historically recognized as "vitamin Bx" for its role in folate synthesis by gut bacteria.

Why we use it:
• Skin & Hair – Supports melanin production and UV protection
• Microbiome Balance – Promotes beneficial bacteria growth
• Antioxidant – Scavenges free radicals in skin tissues
• Protein Utilization – Aids in breaking down amino acids

Can be found in:
Whole grains, liver, mushrooms, and spinach.

The Losoki Difference:
Dual-Action PABA Complex –
✓ Combined with inositol for enhanced bioavailability
✓ Fermented from plant sources (non-synthetic)
✓ Free from sulfa drug cross-reactivity