Ergothioneine

There is insufficient clinical data to support this, so it's recommended to consult a doctor before use.

However, due to its anti-inflammatory properties and positive effects on overall health, it's theoretically possible that moderate intake of ergothioneine may help alleviate menstrual-related symptoms, such as dysmenorrhea and mood swings.

Possibly more effective: Compared to younger people, people over 50 typically face higher levels of oxidative stress and lower endogenous antioxidant capacity. Therefore, the effects of ergothioneine supplementation may be more pronounced.

Reasoning: Studies have shown that ergothioneine levels in the body decline with age, especially after age 50. This may be due to reduced dietary intake or decreased absorption efficiency. Therefore, ergothioneine supplementation can help restore ergothioneine levels to normal, allowing it to better exert its protective effects.

1. Pregnant and lactating women
   The effects of ergothioneine and spermidine on fetal development have not been fully studied. Black truffle extract may contain bioactive substances that interfere with hormonal balance.
   Reference: The International Federation of Gynecology and Obstetrics (FIGO) recommends caution in the use of plant extracts during pregnancy (2021).
2. Children and adolescents (<18 years old)
   Spermidine may affect cell proliferation regulation. The astaxanthin dose (2mg) exceeds the recommended upper limit for children (0.5mg/day).
3. Patients with hepatic and renal impairment
   Combined formulas require hepatic and renal metabolism, which may increase the metabolic burden.
4. Patients with specific medical conditions
   Patients with autoimmune diseases (such as lupus erythematosus): Black truffle extract may activate the immune response.
   Patients with gout or hyperuricemia: Black truffles contain purine derivatives, which may induce elevated uric acid levels.
   Patients with seafood allergies: Astaxanthin may be extracted from Haematococcus pluvialis, posing a risk of cross-allergy. 5. People at Risk of Drug Interactions
5. Drug Interactions: Avoid co-administration with anticoagulants (such as warfarin), as this may increase the risk of bleeding. Consult a physician if using this product with immunosuppressants.
6. Allergy Risk: Use with caution if you are allergic to mushrooms or fungi, astaxanthin (e.g., those rich in it, such as Haematococcus pluvialis and krill), or vitamin B12.

Vitamin B12 and ergothioneine help improve energy metabolism and alleviate fatigue.

No rebound effect after stopping: After stopping ergothioneine, it will remain in the body for three months. As the body metabolizes it, the ergothioneine content in the body will gradually decrease to its original level. It is recommended not to stop taking it suddenly after long-term use. Instead, reduce the dosage to allow the body to adapt and avoid a stress reaction.

The ingredients are natural and safe, with no known side effects. However, it is recommended to take it within the recommended dosage. Please confirm in advance whether it is suitable for your condition.

This product primarily targets antioxidants and immunity, and has limited sleep-improving effects. It is recommended to be taken in the morning.
Taking it before bed may cause mild insomnia.

This product isn't directly targeted at weight loss, but it does help boost metabolism and energy levels.